Microbial CRDMO Solutions with excellence in quality and global regulatory compliance
Recombinant Protein
Recombinant proteins are produced through recombinant DNA technology using microbial expression systems such as E. coli and yeast expression systems. They are widely used in therapeutic proteins, diagnostics, cytokines, enzymes, growth factors, and other biopharmaceutical applications.
Bio-Pharma provides comprehensive recombinant protein expression and production services for a broad range of protein modalities. As an experienced protein production service provider, we support strain development, process optimization, protein purification, analytical characterization, and GMP manufacturing. With a well-established CRDMO platform and extensive project experience, we provide custom protein production solutions to meet diverse requirements across every stage of recombinant protein projects.
Yaohai Bio-Pharma leverages integrated CMC development and cGMP manufacturing capabilities to support recombinant protein production using advanced microbial expression systems, including E. coli expression and yeast expression systems. We select the optimal host platform based on protein characteristics, yield requirements, and downstream development needs.
Recombinant Protein Expression Systems
Leveraging advanced microbial expression systems and integrated CRDMO capabilities, Bio-Pharma supports the development, scale-up, and manufacturing of diverse recombinant protein modalities for research, clinical, and commercial applications.
Recombinant Protein CRDMO Modalities:
Modality 1: Therapeutic Peptides & Hormones
Target Products:Recombinant Insulins, Recombinant Growth Hormones, Recombinant GLP-1, Parathyroid Hormone (PTH), Glucagon, Leptin.Platform Capabilities:We provide tailored microbial expression and purification solutions for hormone and metabolic biologics. Leveraging advanced fermentation, protein refolding, and purification technologies, our platform enables the scalable manufacture of recombinant insulins, growth hormones, GLP-1 analogues, PTH, glucagon, and leptin with high yields, exceptional purity, and consistent product quality from development through commercial production.
Target Products: Virus-Like Particles (VLPs), Recombinant Subunit Vaccines, Recombinant Enzymes.Platform Capabilities:Recognizing that different types of recombinant vaccines demand highly distinct development approaches, our platform supports diverse virus-like particle (VLP) production and vaccine antigen expression. We leverage our robust yeast expression system and advanced fermentation scaling to overcome manufacturing bottlenecks for complex macromolecular structures.
Modality 3: Cytokines & Immune Modulators
Target Products:Recombinant Cytokines, Recombinant Growth Factors, Thrombopoietin (TPO).Platform Capabilities:Accelerate your immunotherapy and cell culture pipelines with our high-yield cytokine production capabilities. Utilizing optimized E. coli and microbial expression systems, we achieve premium biological activity and exceptional purification benchmarks, consistently reducing endotoxin levels to <1 EU/mg.
Service Platform
With a mature microbial CRDMO platform specializing in E. coli and yeast expression systems, we provide comprehensive end-to-end services. From microbial cell banking and robust protein process development to GMP manufacturing and global IND/BLA regulatory support, we are fully equipped to accelerate your drug pipelines from R&D to commercialization.
End-to-End Microbial CRDMO Service Platform for Recombinant Proteins
Yaohai Bio-Pharma Offers One-Stop Recombinant Protein CRDMO Solutions
Yaohai Bio-Pharma delivers tailored solutions for global clients, meeting diverse project requirements with excellence and efficiency.
Proven Project Excellence
Proven track record of over 100 successful projects, spanning preclinical studies and Phase I/II/III clinical trials, including US–China dual submissions and Australian regulatory filings.
Regulatory Compliance Assurance
A robust GMP-aligned quality system with standardized SOPs, fully compliant with global regulatory guidelines across the entire product lifecycle.
Expert Team Support
Powered by industry-leading scientists and cross-functional experts, our team delivers CRDMO projects with speed, precision, and deep technical insight.
