All Categories

Yeast Fermentation for VLP Production

Yeast is a microscopic, single-celled organism that can be seen in the figure below. This tiny and basic thing is everywhere, mostly in the air but also in our own soil and even at arm's length - water. Yeast is super powerful in science and medicine because scientists use it to make important things such as vaccines, which help keep us healthy. They do this in part through the fascinating creation of something known as VLPs.

VLP: virus-like particles The ones that the U.S. has cleared are little constructions of what appear to be viruses but don't actually make you sick. So, they lack all the components that make us ill or infectious. VLPs are a way for scientists to train our immune system on how to fend off actual viruses. That is where the use of a virus looking concoction comes - to help our immune system practice how they would recognize and attack, without really being infected (hence can infect its host chain)!

The Critical Role of Yeast in Producing High-Quality VLPs

One yeast, very good at producing quality VLPs. They have a unique property to generate set of proteins in fast rate which can assemble together for VLPs. By altering yeast cells, scientists can make them express VLPs that appear virtually indistinguishable from the outside of live viruses. This is a very useful attribute because we can teach our immune system how to destroy the viruses, therefore making them extremely effective. That way when our body encounters a real virus, it can draw on that information to fight the invader.

The yeast cells receives new, exogenous genes encoding the viral proteins necessary for forming VLPs. These genes are kind of like a recipe for the yeast. The cells receive these commands and produce the proteins, which are then secreted into the medium. The proteins begin to auto-assemble and VLPs are forming. Scientists then harvest the VLPs produced by the yeast, purify them and incorporate them into vaccines to help protect people against diseases.

Why choose Yaohai Yeast Fermentation for VLP Production?

Related product categories

Not finding what you're looking for?
Contact our consultants for more available products.

Request A Quote Now